Rapid industrialization, urbanization, pollutants emission from vehicles and waste disposal problems are creating environmental pollution in cities which is a serious ecological and public health problem. The conventional remediation technologies are costly, energy consuming and environmentally disruptive, so sustainable and eco-friendly solutions need to be developed. The implementation of green technology phytoremediation, which involves the use of plants to remove, stabilize or eliminate contaminants from soil, water and air, represents a promising solution to combat pollution in urban environments. The purpose of this study is to assess the applicability of indigenous plant species to the sustainable treatment of pollution in urban environment. Being well adapted to the local environmental conditions, native plants have climatic, ecological tolerance, they are low maintenance and have a higher survival rate, thus making them good candidates for long term remediation programmes. The study aims are to evaluate the pollutant accumulation capacity, tolerances, growth performance and ecological importance of selected native species in polluted urban habitats. Special attention is given to the elimination and stabilization of heavy metals, particulates, hydrocarbons and other pollutants from urban areas. The morphological, physiological and biochemical parameters are measured for the assessment of the phytoremediation efficiency and stress tolerance. The findings also emphasize the importance of native plants for enhancing urban biodiversity, ecological balance, beauty, and mitigating urban climate effects (e.g., urban heat islands). The results will help to identify efficient native species for phytoremediation, and will guide the design of sustainable urban green infrastructure and environmental restoration plans.