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VOL. 13, ISSUE 1 (2026)
Effects of methanolic extracts of Balanites Aegyptiaca, Cassytha Filiformis and Boswellia Dalzielii on lipid profile in male wistar rats
Authors
Umar Farouq Zubairu, Maryam Muhammad, Auwalu Sulaiman
Abstract
The effect of methanolic
extracts of Balanite aegyptiaca, Cassytha filiformis and Boswellia dalzielii on
lipid profile parameters in male wistar rats were evaluated. The sub chronic
effect of the methanolic extracts was investigated after daily oral
administration for 21 days at different dose levels (50, 100, and 200 mg/kg BW)
in male wistar rats. The effects on lipid profile [total cholesterol (TC),
total triglyceride (TG) and high density lipoprotein (HDL)] were measured as indices
of toxicity. Results showed that methanolic extracts of Balanite aegyptiaca,
Cassytha filiformis and Boswellia dalzielii generally had
significant(p<0.05) hypolipidemic effect on lipid profile when compared with
the control, which had cholesterol, triglyceride and high density lipoprotein
values 1.78, 1.25, 1.76mmol/L respectively. The result demonstrated that
concentration of total cholesterol in the animals administered with Cassytha
filiformis extract at doses 50, 100 and 200mg/kg body weight were 1.25, 1.31,
1.35mmol/L respectively, total triglyceride concentrations at doses 50, 100 and
200mg/kg were 0.77, 0.49 and 0.76mmol/L respectively and HDL values at doses
50, 100 and 200mg/kg respectively were 0.76, 0.76 and 0.87mmol/L respectively.
These values showed decrease in the level of lipid profile parameters when
compared with the normal control results. From this study it can be concluded
that methanolic extracts of Cassytha filiformis administered at all the doses
had the highest hypo- lipidemic effect at 50mg/kg.
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Pages:513-518
How to cite this article:
Umar Farouq Zubairu, Maryam Muhammad, Auwalu Sulaiman "Effects of methanolic extracts of <i>Balanites Aegyptiaca, Cassytha Filiformis </i>and<i> Boswellia Dalzielii</i> on lipid profile in male wistar rats". International Journal of Multidisciplinary Research and Development, Vol 13, Issue 1, 2026, Pages 513-518
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