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VOL. 12, ISSUE 9 (2025)
Transjugular Intrahepatic Porto Systemic Shunt: A comprehensive review of innovations and future perspectives
Authors
Kothwala Dr. Deveshkumar, Lad HirenKumar, Tandel Yashasvee
Abstract
Portal hypertension is a serious problem of
chronic liver disease, supporting to the life-threatening circumstances such as
variceal bleeding and refractory ascites. A minimally spreading process called
Transjugular Intrahepatic Portosystemic Shunt (TIPS) has been become popular
for treating portal pressure reduction in patients who are not responding to
conventional therapy. This review aims to evaluate the technological evolution,
mechanism of action, clinical indications, and performance outcomes of TIPS,
with emphasis on innovations such as covered stents, advanced procedural
techniques, and future directions. The database PubMed, Embase, and Scopus were
used to perform a through literature review. Involved were pertinent equipment
reports, meta- analyses, and clinical trials executed between 1987 and 2025.
Global guidelines, device evaluations, and randomized controlled trials (RCTs)
were emphasized. The use of ePTFE-covered nitinol stents and hybrid delivery
methods has improved procedure accuracy and patency rates. TIPS relieve the
symptoms of hepatic hydrothorax, Budd-Chiari syndrome, and hepatic hydrothorax,
Budd-Chiari syndrome, and hepatopulmonary syndrome and are more effective than
large volume paracentesis in treating refractory ascites. Nonetheless, certain
restrictions still exist, such as the possibility of hepatic encephalopathy
(HE0, the lack of standardized post-TIPS surveillance, and the scarcity of
paediatric data. Ai-based risk prediction, 3D modelling for pre-procedure
planning, and biodegradable or adjustable-flow stents are examples of novel
approaches currently in development. The primary treatment for problem from
portal hypertension was still TIPS. To maximized results, especially in special
populations and long-term care setting, more developments in device design,
patient selection device, and multicenter trials are required.
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Pages:102-106
How to cite this article:
Kothwala Dr. Deveshkumar, Lad HirenKumar, Tandel Yashasvee "Transjugular Intrahepatic Porto Systemic Shunt: A comprehensive review of innovations and future perspectives ". International Journal of Multidisciplinary Research and Development, Vol 12, Issue 9, 2025, Pages 102-106
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