Background: Eczema has a significant influence on patient's quality of life. It is now well-documented that psychological distress has a role in the onset, escalation, and persistence of skin disease symptoms. Some patients with visible diseases have expressed high degrees of self-consciousness, and it has been reported that this feeling is associated with avoidant coping mechanisms

Method: The present study was carried out with 108 patients diagnosed with eczema and 112 normal people aged range 18-63 years by using the purposive sample method. A between-group design (The independent sample t-test) was employed to study group differences between persons with eczema and normal control on the quality of life.

Result: Result of the study revealed that there is a significant difference between the eczema patients’ group and the normal control group on overall quality of life and also on various dimension of life quality viz., physical symptoms and feelings, daily activities, leisure, work/school, personal relationships, treatment. The result also revealed that eczema patients have poor quality of life in comparison to normal control as high score on DLQI indicates poor quality of life.