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VOL. 12, ISSUE 11 (2025)
Impact of Immunonutrition (Arginine, Glutamine, Omega-3 Fatty Acids) in Critical Illness management
Authors
Ankita Sengupta
Abstract
Immunonutrition — the targeted provision of nutrients with
immune-modulating properties such as arginine, glutamine, and long-chain
omega-3 polyunsaturated fatty acids (PUFAs) — has been investigated as an
adjunctive therapy to modulate inflammation, preserve gut integrity, and reduce
infectious and metabolic complications in critically ill patients. Evidence
from perioperative and ICU trials suggests potential benefits in selected
populations (reduced infections, shorter ICU stays), but results are heterogeneous
and safety concerns (particularly with glutamine in certain ICU cohorts) temper
routine broad application. This review summarizes mechanisms of action, key
clinical trial and meta-analytic findings, dosing and safety considerations,
and practical recommendations for clinicians caring for critically ill adults.
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Pages:26-28
How to cite this article:
Ankita Sengupta "Impact of Immunonutrition (Arginine, Glutamine, Omega-3 Fatty Acids) in Critical Illness management". International Journal of Multidisciplinary Research and Development, Vol 12, Issue 11, 2025, Pages 26-28
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