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VOL. 11, ISSUE 4 (2024)
Study of healing Wistar Rat incision wounds through the use of ointments containing Andaliman fruit extract
Authors
Ren Jiaxuan
Abstract
Andaliman (Zanthoxylum acanthopodium DC) is a
plant that supports the UNESCO Toba Caldera Geopark and is a traditional spice
of the Batak tribe. The content of terpenoids makes it have cultural value and
health potential. Herbal products from andaliman are effective in wound healing
without excessive side effects. Research on Wistar rats shows the potential of
andaliman ointment as a safe natural alternative in health care. The
experimental study was conducted in January 2024 at the Laboratory of
Universitas Prima Indonesia with 25 male Wistar rats divided into 5 groups.
Tests of the effectiveness of Andaliman Fruit ointment in wound healing in
Wistar rats showed significant differences in response to Andaliman extract,
strengthening its potential influence in wound healing. Andaliman Fruit Extract
contains bioactive compounds such as alkaloids, flavonoids, saponins, and
tannins that play an important role in healing incision wounds in white rats.
The optimum concentration for best effectiveness was identified at 9%, showing
results competing with Bioplacenton® in wound healing. In conclusion, Andaliman
fruit has the potential as an effective alternative in healing incision wounds
in white rats, showing results that compete with Bioplacenton®.
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Pages:32-36
How to cite this article:
Ren Jiaxuan "Study of healing Wistar Rat incision wounds through the use of ointments containing Andaliman fruit extract". International Journal of Multidisciplinary Research and Development, Vol 11, Issue 4, 2024, Pages 32-36
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