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VOL. 11, ISSUE 3 (2024)
Analytical method development and validation of fluvoxamine maleate in bulk and its formulation by Uv spectroscopy
Authors
B Bhadru, G Akhila, M Himabindhu, K Hemanth, T Rama Rao
Abstract
The development of the UV Spectrophotometry method for Fluvoxamine maleate
quantification is included in the current study effort. A unique, straightforward,
and accurate method for estimating the amount of Fluvoxamine maleate in bulk has
been devised dosing form for pharmaceuticals. The ideal circumstances for the drug
analysis were determined. Beer's law is followed when using 0.1N hydrochloric
acid as a solvent with a concentration of 5–10 µg/ml at λ max of 246 nm. The absorbance
and concentration have a linear relationship, as indicated by the calibration curve.
With a r2 of 0.9999, the line equation Y = 0.026x + 0.0803 was
discovered. The developed procedure was proven to be exact and accurate when
validated in accordance with ICH requirements. Fluvoxamine maleate can be accurately
estimated using the suggested method for both pharmaceutical dose forms and bulk
forms. The analysis's conclusions were supported by recovery studies and
statistical validation.
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Pages:18-21
How to cite this article:
B Bhadru, G Akhila, M Himabindhu, K Hemanth, T Rama Rao "Analytical method development and validation of fluvoxamine maleate in bulk and its formulation by Uv spectroscopy". International Journal of Multidisciplinary Research and Development, Vol 11, Issue 3, 2024, Pages 18-21
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