ARCHIVES
VOL. 11, ISSUE 2 (2024)
Efficacy test of red betel leaf ethanol extract ointment on the healing of second-degree burns in wistar rats
Authors
Huang Chengtuan, Fioni
Abstract
Burn injuries can occur through direct contact or exposure to thermal,
electric, chemical, or radiation sources. The management of burn victims often
involves the application of topical preparations to treat wounds. Red betel
leaves (Piper scrotum Ruiz & Pav) are considered a potential remedy for
burns due to the antibacterial properties of their essential oil, which
accelerates the healing process. This experimental research, utilizing a
pre-test and post-test control group design, was conducted in January 2024 to
investigate the phytochemical content and effectiveness of red betel leaf
essential oil in treating degree II burns in Wistar rats (Rattus norvegicus).
With Wistar strain mice as samples, totaling 20, data analysis included One-Way
Anova differential tests followed by a post-hoc test. Phytochemical screening
of fresh red betel leaves revealed the presence of alkaloids, flavonoids, and
tannins. The epithelialization period exhibited no significant differences
between the red betel ointment groups (25% and 50%) and the standard group. The
wound-healing effect of red betel leaf ointment (25% and 50%) and nebacetin
ointment showed significant differences, with the red betel leaf ointment at
50% demonstrating a superior wound contraction rate compared to nebacetin
lotion. However, neither red betel leaf ointments nor nebacetin ointments
differed significantly regarding the epithelialization period parameter.
Download
Pages:125-128
How to cite this article:
Huang Chengtuan, Fioni "Efficacy test of red betel leaf ethanol extract ointment on the healing of second-degree burns in wistar rats". International Journal of Multidisciplinary Research and Development, Vol 11, Issue 2, 2024, Pages 125-128
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.