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VOL. 11, ISSUE 2 (2024)
Exploration of the ability of turmeric cream with ethanol extract in healing incision wounds in wistar rats
Authors
Chen Longjun, Liena
Abstract
The shape of the wound is different depending on the cause; some are
open and closed, and the healing consists of several phases, namely the
inflammatory phase, proliferative phase, and maturation phase. Several sources
state that turmeric rhizome extract is effective in wound healing. This study
aimed to test the potential of turmeric rhizome extract to be effective in
wound healing. This type of research is experimental with a pre-test and
post-test group-control design approach, and it was conducted in January 2024.
The samples used were turmeric rhizomes (Curcuma Longa) and male white rats.
Determination of sample size according to Frederer’s formula, so the number of
pieces was 25 rats, the division of 4 treatment groups and one control group.
The data will be analyzed for normality and continued with the ANOVA test. The
results of turmeric extract contain chemical compounds of alkaloids,
flavonoids, saponins, and tannins. Based on the research, turmeric ethanol
extract (Curcuma Longa) with a 9% concentration showed optimal efficacy in
healing incision wounds in white rats, reaching a comparable healing percentage
of 93% on day 15 compared to the positive control, Bioplacenton®. The extract
contains bioactive compounds like alkaloids, flavonoids, saponins, and tannins,
contributing to its wound-healing properties. These results support the potential
use of turmeric ethanol extract as an effective alternative in supporting the
wound healing process.
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Pages:129-133
How to cite this article:
Chen Longjun, Liena "Exploration of the ability of turmeric cream with ethanol extract in healing incision wounds in wistar rats". International Journal of Multidisciplinary Research and Development, Vol 11, Issue 2, 2024, Pages 129-133
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