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VOL. 11, ISSUE 2 (2024)
Performance test of turmeric ethanol extract on pancreatic amylase enzyme activity in doxorubicin-induced wistar rats
Authors
Wu Dingyong
Abstract
Turmeric (Curcuma longa Linn), a member of the Zingiberaceae family,
contains curcuminoids known for their therapeutic properties in treating and
preventing various human diseases. This experimental study aims to establish a
correlation between the independent variable, turmeric ethanol extract, and the
dependent variable, the reduction in fasting blood glucose levels in January
2024. Data normality was assessed using the Shapiro-Wilk method, and for
normally distributed data (P > 0.05), the analysis proceeded with one-way
ANOVA to determine average group differences. In significance (P < 0.05),
the Post Hoc Tukey HSD test was employed to identify specific treatment variations.
Alternatively, the Kruskal-Wallis test was applied for non-normally distributed
data. The results indicate that Curcuma longa ethanol extract at doses of 200
mg/kgBB, 250 mg/kgBB, and 300 mg/kgBB significantly reduces blood glucose
levels (P < 0.05) compared to the negative control group, administered only
with CMC-Na and doxorubicin. Furthermore, Curcuma longa extract at doses of 200
mg/kgBB, 250 mg/kgBB, and 300 mg/kgBB significantly reduces HbA1c levels (P
< 0.05) compared to the negative control group under the same conditions.
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Pages:99-103
How to cite this article:
Wu Dingyong "Performance test of turmeric ethanol extract on pancreatic amylase enzyme activity in doxorubicin-induced wistar rats". International Journal of Multidisciplinary Research and Development, Vol 11, Issue 2, 2024, Pages 99-103
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