ARCHIVES
VOL. 11, ISSUE 11 (2024)
Evaluation of antioxidant, anti-inflammatory and anticancer activities of root stock of Monochoria vaginalis – An in vitro study
Authors
Latha B, Nimisha SN
Abstract
Monochoria vaginalis
is a plant belonging to the Pontederiaceae family known to have several
medicinal properties. It is a weed found in rice (Oryza sativa) fields and is
used as a vegetable. Even though the plant root stock and leaves have cooling,
bittersweet, aromatic and diuretic properties, some of the phytochemical and
pharmacological properties in this plant still remain unexplored. The objective
of the present study was to explore the antioxidant, antimicrobial and
anticancer characteristics of the methanolic extract of root stock of Monochoria
vaginalis through in vitro assays. Phytochemical studies were
carried out using three different solvents such as petroleum ether, chloroform
and methanol. DPPH radical scavenging assay, trypsin inhibitory assay, protein
denaturation assay, MTT assay and apoptosis detection by acridine orange and
ethidium bromide double staining method were carried out. Phytochemical analysis
revealed the presence of phenols, flavonoids, alkaloids, glycosides, terpenoids
and steroids. Methanolic extract exhibited significant antioxidant and anti-inflammatory activities. Cytotoxicity studies
showed significant mortality against HeLa cell lines. Extracts possess
significant anti-inflammatory and anticancer activities, validating its
traditional uses. This study provides evidence for the plant's potential as a
natural antioxidant, anti-inflammatory and anticancer agent.
Download
Pages:13-19
How to cite this article:
Latha B, Nimisha SN "Evaluation of antioxidant, anti-inflammatory and anticancer activities of root stock of <i>Monochoria vaginalis</i> – An <i>in vitro</i> study". International Journal of Multidisciplinary Research and Development, Vol 11, Issue 11, 2024, Pages 13-19
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.