The research was conducted in Bojonegoro Regency which by UTM coordinates is located at 569187.51 until 618964.78 and 9226764.44 until 9183751.81. The geophysical method used is gravity method by looking for the distribution of the density. The data used is gravity disturbance data downloaded from the official website of Global Gravity Model Plus (GGMplus 2013) and Earth Residual Terrain Model (ERTM2160). We applied the moving average and horizontal gradient derivative. The aims of study area to separate the regional and local anomaly and to detect the structural geology or contact lithology in Bojonegoro area. Results of research are Lithology of Bojonegoro area is not only influences by local but regional as well. Horizontal Derivative could detected the fault structure in Kendeng Hills, Anticlines in Kawengan and several fault souronding Khayangan Api Abadi area.