Histopathological effect of endosulfan on the muscles of Clarias gariepinus (Burchell, 1822) (Siluriformes: Clariidae)
P Verma, D B Sawarkar, S Kurikose
Pesticides are transported into aquatic ecosystems, where they enter organisms via food webs and water contact. Given the significance of fish in the food chain, studies on the impacts of pollutants on fish are crucial in determining the consequences of pollutants on human health. For the management of insect pests, Endosulfan is an organochlorine insecticide that is neurotoxic. Organochlorides are the most prevalent toxin in the aquatic environment. The aquatic food chain is disrupted by the application of this insecticide, which is particularly dangerous to fish. Fish tissue can be examined histopathologically to identify disease-related early warning signs as well as long-term damage to cells, tissues, and organs. We report here that Endosulfan exposure caused significant histopathological changes in the muscle, including muscle fibres splitting, broken myofibrils, disintegration of the muscle bundle, and gap formation in myofibrils, at various sub-lethal concentrations (0.216, 0.43, and 0.86 g/l) for various time periods (5, 10, and 15 days). With a rise in the time and concentration of Endosulfan, there is a corresponding increase in necrosis, inflammatory reactions, infiltration of blood cells, and dystrophic alterations demonstrating separation of the muscle bundle of Clarias gariepinus (Burchell, 1822) muscle.
P Verma, D B Sawarkar, S Kurikose. Histopathological effect of endosulfan on the muscles of Clarias gariepinus (Burchell, 1822) (Siluriformes: Clariidae). International Journal of Multidisciplinary Research and Development, Volume 9, Issue 11, 2022, Pages 12-15