International Journal of Multidisciplinary Research and Development

International Journal of Multidisciplinary Research and Development


International Journal of Multidisciplinary Research and Development
International Journal of Multidisciplinary Research and Development
Vol. 8, Issue 7 (2021)

Biochemical and sonological profile in patients with incidentally detected non alcoholic fatty liver disease


Vishwas K, C Ramachandra Bhat, Kamalesh TN, Amoghasiddha S Jyoti

Background: Non-alcoholic fatty liver disease (NAFLD) is the upcoming leading cause of chronic liver disease and its prevalence is increasing worldwide. It is a spectrum of liver diseases that ranges from simple steatosis to a progressive form of liver disease called non-alcoholic steatohepatitis (NASH). NAFLD patients are at risk of progressing to NASH and ultimately cirrhosis; they are also at higher risk of cardiovascular diseases (CVD), including coronary heart disease and stroke. The aim of the present study is to co relate the association of lipid profile abnormalities in patients with different grades of fatty liver. Aim: 1. To evaluate risk factor, association between sonographically diagnosed non-alcoholic fatty liver disease and biochemical derangement. 2. To estimate prevalence of non-alcoholic fatty liver in our population coming for general health checkup. Materials and Methods: A total of 100 cases diagnosed with Non Alcoholic Fatty liver disease (NAFLD) on ultrasound were divided in to 3 groups based on sonological grading. They were further divided based on age into two groups, of which 55 are males, and 45 are females. All patients were subjected to complete history taking and clinical examination, fasting lipid profile and other routine blood investigations. Results: In this study of 100 patients, 52 % are grade I, 30 % are grade II, and 18 % are grade III NAFLD. Serum TG, TC, LDL-C, and HDL-C levels were abnormally raised in 57%, 55%, 60%, and 59% patients, respectively. Forty two cases were diabetic, twelve individuals consume alcohol, and Thirty three are overweight in the present study population. Conclusion: The sonological grade of the Fatty liver correlate with the biochemical lipid abnormalities, the higher the grade of fatty liver more is dyslipidemia.
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How to cite this article:
Vishwas K, C Ramachandra Bhat, Kamalesh TN, Amoghasiddha S Jyoti. Biochemical and sonological profile in patients with incidentally detected non alcoholic fatty liver disease. International Journal of Multidisciplinary Research and Development, Volume 8, Issue 7, 2021, Pages 144-147
International Journal of Multidisciplinary Research and Development International Journal of Multidisciplinary Research and Development