Antimicrobial and anti-diarrheal activity of some Sudanese medicinal plants from anacardiaceae family
Tahani Khidir M, Ali Ahmed I, Abdel Azim Ali A
In the present study, methanolic extract of Rhus abyssinica, Heeria insignis and Lannea schimperi leaves, stem and roots were evaluated by employing in vitro antimicrobial and anti- diarrheal activity. Standard methods were adopted for testing the bioactivity of the components towards four bacterial species (Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus), two fungal species (Aspergillus niger and Candida albicans), two protozons (Entamoeba histolytica and Giardia lamblia) Methanol extract of Lannea schimperi stem showed high antibacterial activity against Bacillus subtilis (27 mm) as compared with the standard antibiotics ampicillin (20 mm) and gentamicin (25 mm). %). Extract from Lannea schimperi leaves had potent antigiardial and antiamoebic activities (IC50 ≤ 100 µg/ml) against Giardia lamblia and Entamoeba histolytica, 80.82 and 92.21 µg/ml respectively.