Background: Shoulder Impingement syndrome (SIS) is the second common musculoskeletal pain condition. Shoulder girdle muscle imbalance, tight posterior capsule have been implicated as contributing factors. Objective: The purpose of this study was to investigate the effect of shoulder stability exercises (SSEs) on cervical proprioception (active joint angular reproduction, AJAR at 30^o flexion and extension) in patients with mechanical cervical and shoulder pain. Subjects and methods: Eleven patients (one group) had participated in this study, with age ranged from 27 to 42 years. Each patient was assessed for cervical proprioception (active joint angular reproduction, AJAR at 30^o flexion and extension) using bubble inclinometer. Results: There was statistically significant effect of SSEs on cervical proprioception (active joint angular reproduction, AJAR at 30⁰, only for flexion (P=0.05), but not for extension (P=0.12) in patients with mechanical cervical and shoulder pain. Conclusion: SSEs could affect cervical proprioception in patients with mechanical cervical and shoulder pain.