The economy of any country depends on its human resources. Currently, the 2019 novel coronavirus disease (COVID-19) is the most affecting infectious disease. The number of active cases and deaths are still increasing in India. COVID-19 has affected human life, socio-economic development and national relations up to a great extent. It is a risk for senior citizens and people with several health issues such as cancer, diabetes, heart related problems. The World Health Organization (WHO) has formally declared COVID-19 to be a public health emergency in global level. As of 6^th May 2020 Maharashtra, was found to be the most affected state in India followed by Gujarat and Delhi. Due to the infection chain ratio, the positive cases are increasing each day in each affected states of India. Indian government tried the lockdown concept to break the infection chain ratio affected by COVID-19. The aim of the research is to analyze the spatial distribution and Impact assessment of the COVID-19 for human health using GIS software. Geographic Information Systems (GIS) technologies have played an important role in the spatial information, spatial tracking of confirmed cases, active case, death and discharge case as well as prediction of magnitude of the spread. Therefore, monitoring and planning using geospatial analysis is very important to control COVID-19 spread in the country.