A cross sectional study of hepatic derangements in type 2 diabetes mellitus patients of a tertiary care teaching hospital in Karnataka
Dr. Monika MP, Dr. Gireesh, Dr. Prajwal Kumar US
Introduction: Nonalcoholic fatty liver disease is one of the major cause for chronic liver disease globally. Type 2 diabetes is a thought to increase the risk of mortality in patients with NAFLD (Non Alcoholic Fatty Liver disease). Hence diagnosis of fatty liver is important in diabetes mellitus. The objective was to assess the proportion of patients with nonalcoholic fatty liver disease in diabetes and also to study the biochemical derangements in them. Materials and Methods: A total of 200 diabetic patients were selected randomly from a tertiary care teaching hospital. Patients were examined and blood investigations were done on them after obtaining written informed consent and permission from ethical committee. Results: 65% of the patients had nonalcoholic fatty liver disease. Patients with fatty liver disease had elevated total cholesterol, LDL levels, triglycerides and decreased HDL. The Mean SGOT/SGPT ratio was more than 1 in them. The mean BMI was also found to be higher when compared to those without fatty liver disease. Conclusion: The proportion of patients with NAFLD in diabetes is higher and deranged lipid and hepatic parameters in diabetic patients may point to the diagnosis of NAFLD.
Dr. Monika MP, Dr. Gireesh, Dr. Prajwal Kumar US. A cross sectional study of hepatic derangements in type 2 diabetes mellitus patients of a tertiary care teaching hospital in Karnataka. International Journal of Multidisciplinary Research and Development, Volume 7, Issue 3, 2020, Pages 83-85