Effect of early iron supplemenataion on haemoglobin, indices, ferritin and growth parameters of low birth weight infants
Dr. Raneta Kurian Paul, Dr. Anjali CS, Dr. Vijaykumar B
LBW infants have diminished iron reserves and are at greater risk of developing iron deficiency Objective: To study hematological status at birth, 1 month, and 3 month in low birth weight infants.To start early iron supplementation and evaluate its effect on, Hb, indices and Serum Ferritin levels in exclusively breastfed non morbid LBW infants. Effect of iron supplementation on growth parameters. Study design: Prospective case control study. Study setting: Department of pediatrics KVG Medical college and hospital. Methodology: This randomized case control study was carried out from June 2019 to December 2019 in the neonatal unit and high risk follow up clinic of Department of Pediatrics, K.V.G Medical college and hospital, Sullia. Result: Initially 58 newborns satisfying inclusion criteria were enrolled into the study. • Initial enrollment was 58, out of these at 1 month follow up 40 subjects satisfying the inclusion criteria came for follow up. Among the IS (case) group 33% were of Preterm (AGA) neonates whereas 67% were FT (SGA). Both hemoglobin and serum ferritin values difference in IS and CONTROL groups were found statistically not significant after 2 months of iron supplementation in IS group. All three parameters did not show significant statistical difference (p>0.05) at 3 month after iron supplementation which can be seen in table 8. So both the groups were comparable. Is it iron supplementation promoted the better weight gain and nullify the difference from control group which was present at 1 month. Difficult to interpret because of small sample size. Conclusion: The present study concludes that early iron supplementation at 4 weeks in a therapeutic dose (3 mg/kg/d) in exclusively breastfed non morbid LBW & lt;2000gms infants results in no significant difference in hemoglobin, ferritin and growth status after 8 weeks of supplementation. Larger studies need to be carried out to answer the need of iron supplementation and at what age in full term or near term LBW babies in our country who are predominandy small for gestational age.