International Journal of Multidisciplinary Research and Development

International Journal of Multidisciplinary Research and Development


International Journal of Multidisciplinary Research and Development
International Journal of Multidisciplinary Research and Development
Vol. 6, Issue 9 (2019)

Endonasal Dacryocystorhinostomy with Mitomycin C Application


Abdelaziz Elsherif, Gamal Yuosof, Ahmad Abd-Elkarem, Hesham Gawesh

Objective:Present study was designed to compare the outcome results of endonasal endoscopic dacryocystrhinostomy (DCR) with or without Mitomycin C (MMC) application. Methods: 80 patients with nasolacrimal duct obstruction. They were divided into two equal groups according to the planned surgical intervention technique. Group A: Included 40 patients with nasolacrimal duct (NLD) obstruction who underwent endonasal endoscopic DCR with (MMC) application. Group B: Included 40 patients with NLD obstruction who underwent endonasal endoscopic DCR without (MMC) application. All cases underwent full history taking, clinical examination, laboratory investigations; surgical intervention and follow up for 6 months postoperatively. Results: In the present study, group(A) DCR with MMC application it was found that the success rate was reported in 37 cases (92.5%) and failure in 3 cases (7.5%); while in group (B) DCR without MMC application it was found that the success rate was reported in 33 cases (82.5%) and failure in 7 cases (17%). Conclusion: Results of the present study revealed that, endoscopic DCR with MMC application had a comparable success rate over endoscopic dacryocystrhinostomy (DCR) without MMC application and had advantages of having a higher success rate, less intraoperative and postoperative complication.
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