The childhood period is vital because of socialization process by transmission of attitude, customs and behavior through the influence of family and Community. In India about 35% - 40% of total population is children below 15 years of age. This group is considered as special risk group as they are vulnerable to various health problems. Children always need special care to survive. Children are not like adult, physiologic, cognitive and psychosocial differences affect child’s perception reaction to the illness or injury, communication pattern and coping abilities. To determine child health status and individual needs, knowledge of normal growth and development, careful observation of behavior and physiologic cues and listening to the primary care givers are important. A pediatric emergency is a serious condition that threatens the life of an infant, child, teen or young adult, thus requires immediate medical attention. Pediatric emergencies can be caused a particular illness, an injury or by ingesting a foreign object or poison. Burns are common and serious childhood injury causing prolonged effect on growing child with various complications and fatal prognosis. Accurate assessment of a child with an acute illness or injury requires special knowledge and skills. The majority of children presenting in the ED have mild moderate illness and injury and remain alert. About one in four children under the age of 16years will attend emergency department (ED) at some time in their childhood. The pediatric emergency care applied research network was developed to increase pediatric research. However; participation by emergency nurse has been limited. Research statement: A Descriptive study to assess the knowledge regarding selected pediatric emergencies among staff nurses at selected pediatric hospitals, Kolhapur. Objectives of study To assess the knowledge regarding pediatric emergencies among staff nurses. To find out an association between knowledge score with selected sociology -Demographic Variables. Research Methodology: In the present study Descriptive survey approach is used to assess knowledge regarding pediatric emergencies among staff nurses of selected pediatric hospital. Survey research design is used. 50 samples were selected. Purposive sampling technique was used. Data was collected by semi structured questionnaire. The knowledge score was classified into 3 categories. Good, average and poor. Descriptive and inferential statistics was used to analyze data and for interpretation. Association of knowledge regarding pediatric emergencies with selected demographic variables was assessed using chi-square test. 4% staff nurses having good knowledge about pediatric emergencies. 50% staff nurses were having average knowledge about pediatric emergencies and 46% staff nurses were having poor knowledge about pediatric emergencies. Result: 4% staff nurses having good knowledge about pediatric emergencies. 50% staff nurses were having average knowledge about pediatric emergencies and 46% staff nurses were having poor knowledge about pediatric emergencies. Chi-square test is there is significant association between knowledge and age, sex, Residence of staff nurses, qualification, experience of staff nurses, pediatric experience of staff nurses, experience of managing pediatric emergencies and research experience of staff nurses, we’re found significant at 0.0003 levels. Conclusion: Result of this current study suggests that we should need to continuing education and clinical experience helps to staff nurses gain knowledge and prevent complication.