The objective of this study were to determine the pre-weaning kids mortality of the Damascus cyprus goats in the Eastern Sudan and it's conducted during the period extending from 2014 to 2016, included two district seasons cool dry(Dec-Feb) and hot dry March-May) season(Winter and Summer) on 444 kids born from 336 parent stock the number of kids died were 63 kids during the study. Data collected were used to evaluate the overall means weight, mortality percent in winter and summer, mortality percent at the first week, causes of mortality. The overall means weight of the Damascus cyprus kids were (3.96±0.39) Kg The overall mortality percent in winter were 11.6%, in summer were 17.5%, in both seasons winter and summer were 14.2 %. At the first week the mortality were 30.2 % followed by the second week 19% while in the third week were 12.7 % in fourth week were 11.1% and its reduced gradually till reach 4.7 % in eight weeks at weaning ages. then were reduced gradually with the increase of age. Mortality percent in winter were less comparing with in summer this might be due to environmental condition is favorable and no heat stress. The major causes of kid mortality identified during this study diarrhea was the most frequently suspected cause of mortality (44.4%); followed by weakness (27%), inadequate nutrition (12.6%), environmental condition (8%).