International Journal of Multidisciplinary Research and Development

International Journal of Multidisciplinary Research and Development


International Journal of Multidisciplinary Research and Development
International Journal of Multidisciplinary Research and Development
Vol. 6, Issue 7 (2019)

Synthesis, characterization and biological studies on some metal (II) complexes with Schiff base [(4-chlorophenyl) imino]-3,3-dimethylcyclohexan-1-one


Amna Alameldeen H, Elmugdad Ahmed A, Mohammed Suliman Ali

A new Schiff base ligand [(4-chlorophenyl)imino]-3,3-dimethylcyclohexan-1-one has been synthesized by condensation between dimedone and 4-chloroaniline in the molar ratio 1:1. This synthesized ligand was used for complexation with different metal ions like Fe (II), and Pb (II), by using a molar ratio of ligand: metal as 2:1 in ethanol. The ligand and metal complexes have been characterized by melting point, NMR (1H and 13C), UV–vis spectroscopy, FTIR, MS, and molar conductivity studies. In conductivity experiments, all metal chelates showed to be non-electrolytic in nature. The IR results demonstrate that the co-ordination sites are the nitrogen atoms of the azomethine and the oxygen atoms of the carbonyl groups. The anti-microbial activities of both the ligand and their complexes were screened against two Gram-positive bacterium (Staphylococcus aureus and Bacillus subtilis) and two Gram-negative bacterium (Escherichia coli and Pseudomonas aeruginosa). The anti-fungal activity was screened against Candida albicans, the results show that the metal complexes are more biologically active than the ligand.
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How to cite this article:
Amna Alameldeen H, Elmugdad Ahmed A, Mohammed Suliman Ali. Synthesis, characterization and biological studies on some metal (II) complexes with Schiff base [(4-chlorophenyl) imino]-3,3-dimethylcyclohexan-1-one. International Journal of Multidisciplinary Research and Development, Volume 6, Issue 7, 2019, Pages 22-28
International Journal of Multidisciplinary Research and Development International Journal of Multidisciplinary Research and Development