Black stain is a type of extrinsic discoloration of the tooth on the gingival margin. Black stain is hard to be wiped off by daily cleaning via toothbrushing, and tends to recurred after professional hygiene. The most effective therapies seem to be lactoferrin, diode laser, laser nd:YAG and phototherapy. A 50 years old female patient with good health condition came to our attention due to the recurrent presence of black stains on the surfaces of the teeth. We decided to carry out a laser therapy session, after placing the fluoride gel on the surfaces of the teeth, diode laser irradiation was performed with wavelength 970 nm, power of 1.5W and for a time of about 10 second for tooth. In addition, lactoferrin tablets were prescribed. The patient at the control after 60 days has had an important reduction of the black stains.