Background: Sprint runners in track and field events must run a given distance with maximal effort. Running requires a progressively increasing speed with coordinated contraction of muscles, accelerating the body forward at an increasing velocity. Kinesio taping is widely accepted by professional sprint runners to improve performance during competitions and training. Aim: To determine the effectiveness of facilitatory and inhibitory kinesio taping technique in healthy collegiate sprint runners. Objective: To see the effect of kinesio taping on running time in healthy collegiate sprint runners. Methodology: 30 male participants were recruited in the study. The age group of the participants was 18-24 years. The participants were told to run 100 meters without kinesio taping and the time was recorded. Then the participants were told to run 100 meters with kinesio taping on quadriceps and hamstrings which was applied 24 hours prior to the performance and then the time was recorded. Results: Mean of pre intervention was 15.99 ±1.904 seconds and post intervention was 14.79±1.507 seconds. Conclusion: In this study, it was concluded that there is a significant improvement in sprint running time after applying kinesio taping on healthy collegiate sprint runners. Conclusion: In this study, it was concluded that there is a significant improvement in sprint running time after applying kinesio taping on healthy collegiate sprint runners.