Background: Pressure Pain Threshold is the sensitivity towards pressure which is affected by awkward postures, spinal pathology, muscle hyperalgesia and new methods are researched to detect and measure this via pressure algometer. Dental profession is highly susceptible in developing musculoskeletal disorders with decreased sensitivity to pressure, therefore elicit pain early. Hence, physical therapy interventions along with creating awareness amongst Dentist are essential. Objective: The aim of the current study is to determine the immediate effect of thoracic distraction on pressure pain threshold between dental first year students and dental interns. Methodology: A simple random sampling of 40 female dental students, which were divided into two groups with 20 participants in each group. Where group A included dental first year students while group B dental interns. Both the groups were given Thoracic Manual Distraction and PPT was measured before and after the. Results: Pressure Pain Threshold showed significant increase in group A after the thoracic distortion (‘t’= 6.26, ‘p’= <0.01) while in group B it was not significant (‘t’=0.96, ‘p’= >0.05). But the immediate post intervention between two groups was considered significant (‘t’=4.87, ‘p’= <0.01) Conclusion: Thoracic manual distraction was extremely significant in both the groups but, the dental first year students showed high PPT as compared to the interns.