Uganda Business and Technical Examinations Board administered and marked on the spot practical ICT papers in the revised TVET curricular in all examination centers in November 2016 and 2017 country wide. This study explored the different challenges and opportunities encountered during these assessments using qualitative survey research design. Data were collected using questionnaire from practical ICT examiners. Low computer to student ratio, inadequate working space and power supply interruptions were the major challenges, while Increased paid up assignments for examiners, chances to learn computers by students, increased grants to examination center and demand for computers in the market presented opportunities. Most ICT instructors benefited from the opportunities while the challenges were institutional and beyond the control of the Board. Availing solar & electric generators, purchase of additional computers by centers in phase manner and hiring of trained ICT laboratory technicians could address most of the challenges.