Physically inactive individuals increase in India is due to modernization and it is rapidly increased in urban areas. Exercises are having a propensity to alter the blood vessel changes and it dilates the vessels and promotes more circulation to the part which was under exercises. There are various exercises which are prescribed for the patients with low back pain, among these exercises the core stability is recently added, although there are various benefits are found while applying core stability exercises for the low back pain, their effect on cardiovascular system is not identified and well studied. So this study identifies the effect of core stability exercises on cardiovascular parameters in physically inactive individuals. Experimental study design with 50 physically inactive individuals were recruited using the international physical activity questionnaire (short form), they all advised to do a set of core stability exercises, all the exercises were conducted for 4 times a week and the study organized for two weeks. The data were collected on the first visit of the patient and immediate post exercises, at the end of first week and end of second week. The data were collected through Sphygmomanometer for systolic and diastolic blood pressure and pulse oximetry for heart rate. The collected data was analyzed using SPSS 21.0. The result of the study identifies that the F value of Heart rate is 440.34, 47.29 and 72.82 for the Systolic and Diastolic Blood pressure respectively. There was a significant differences identified between the groups. This study concludes that there is a significant rise in the heart rate and blood pressure following exercises, but the elevation of these cardiac parameters will tend to reduce following regular exercises.