Objectives: To assess LV dyssynchrony in hypertensive patients with normal LV systolic function using Tissue Doppler Imaging (TDI) technique. Methods: The study included 125 persons (100 patients and 25 persons as control group). All subjects underwent full history taking, complete clinical examination, echocardiographic examination for calculation of LV EDD and ESD by M mode, EF by Simpsons method, M mode and 2D eye balling, E/A, Maximum (T-S), (T-Q max), septal lateral delay by TDI Results: Among study population 46 female (46.0%) and 54 male (54.0%) with mean age (53.530 ± 6.802), 52 patients (52%) were had proven left ventricular mechanical dyssynchrony. There is statistically significant positive correlation between HTN and LV mechanical dyssynchrony (P-value < 0.001). Conclusion: Patients with systemic hypertension but without clinical heart failure often demonstrate LV systolic and diastolic dyssynchrony by TDI. The severity of dyssynchrony is significantly related to LV mass, left atrial volume, and LV remodeling. Systolic and diastolic dyssynchrony may identify hypertensive patient at risk for the development of heart failure either (systolic & diastolic), and who may benefit from more intensive hypertension control at an earlier stage in their disease process.