The present study aimed to study the Adjustment, Academic Anxiety and Self-Confidence of senior secondary school students in relation to their Life Skills. It was taken from Panchkula, Kurukshetra, Kaithal, Yamunanagar and Ambala districts of Haryana. It comprised of 250 girls and 250 boys from these schools. Findings show that there exists positive and significant relationship between Life Skills and Adjustment of senior secondary school students. Life Skills is positively and significantly related to Self-Confidence in senior secondary school students. There exists negative and significant relationship between Life Skills and Academic Anxiety of senior secondary school students. Students having better Life Skills will have less Academic Anxiety.