Stress is an unavoidable part of today's express life. In this age of globalization and liberalization of the economy, competition among organizations has increased. Person whether a child, adult, men, women, employed and unemployed everyone is facing stress in his / her own way. Today’s life is full of challenges. In everyday life each and every one comes across many problems and situations. Some of them act as a source of inspiration for us and some causes challenges. It is the human nature to face the challenges boldly or to escape from it. Therefore this study investigated that the opinion of secondary school teachers towards occupational stress. The design of the study survey method was adopted and 310 samples are taken (161 male and 149 female) from secondary school teachers who working in the Salem district in Tamil Nadu. Standardized tool (Teacher Stress Scale) was used to collect data from the sample and both descriptive analysis (Mean and Standard Deviation) and differential analysis (‘t’ and ‘F’ - test) have been applied to analyses the data. The results obtained revealed that the secondary school teachers have average stress in their occupation.