International Journal of Multidisciplinary Research and Development

International Journal of Multidisciplinary Research and Development


International Journal of Multidisciplinary Research and Development
International Journal of Multidisciplinary Research and Development
Vol. 4, Issue 10 (2017)

Morphometric study of fourth ventricle indices in normal subjects by computed tomography


Akanksha Singh, AK Singh, Himani Singh

Aim: The present study aimed to find range of fourth ventricle indices, their variation with age and gender in apparently normal subjects.
Material and Methods: With the Institutional ethical committee clearance, soft copies of head CT scans of two hundred subjects (96 males, mean age 38.31 ± 14.16 yrs., and 104 females, mean age 36.36 ± 16.74 yrs.) were subjected to morphometric analysis of fourth ventricle’s height and width using dicom image software. Mean, standard deviation, ranges were calculated. Two sample independent student t -test, Pearson’s correlation coefficient and Regression analysis were applied to find the gender variation.
Results: The 4th ventricle height of all subjects ranged from 6-12 mm with mean (± SD) 8.96 ± 1.24 mm and median 9 mm. In females, it ranged from 6-12 mm with mean (± SD) 8.59 ± 1.20 mm and median 9 mm while in males, it ranged from 7-12 mm with mean (± SD) 9.36 ± 1.17 mm and median 9 mm. The mean of 4th ventricle height of males was comparatively higher than females. Comparing the mean of 4th ventricle height between two groups, Student’s t test showed significant difference and higher (8.3%) height in males as compared to females (8.59 ± 1.20 vs. 9.36 ± 1.17, t=4.64, p<0.001). Similarly, the 4th ventricle width of all subjects ranged from 6-13 mm with mean (± SD) 9.79 ± 1.19 mm and median 10 mm. In females, it ranged from 6-12 mm with mean (± SD) 9.39 ± 1.14 mm and median 9 mm while in males, it ranged from 8-13 mm with mean (± SD) 10.21 ± 1.09 mm and median 10 mm. The mean of 4th ventricle width of males was comparatively higher than females. Comparing the mean of 4th ventricle width between two groups, Student’s t test showed significantly different and higher (8.0%) width in males as compared to females (9.39 ± 1.14 vs. 10.21 ± 1.09, t=5.13, p<0.001) The 4th ventricle width of all the subjects was comparatively higher than the height of the 4th ventricle in both the genders and was more in males as compared to females.
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