Background: Autism is a neurodevelopmental disorder that impacts typical childhood activities, such as socialization, and is often characterized by displays of repetitive and stereotyped patterns of behavior. These children suffer from behaviors that include extreme aloneness, failure to assume anticipatory postures, delayed or deviant language, and a limited range of spontaneous activities and lack of socialization. Objectives: To find out the effectiveness of group therapy on social interaction in children with Autism. Methodology: Sample data constituted of 34 children (28 males, 6 females) aged 5-15 years who then assessed for Autistic symptoms on the basis of Indian autistic assessment scale by assessing therapist. The Interventional therapist then planned the group therapy for the next 4 weeks. Pre and post therapy assessment by the Indian autistic assessment scale were analyzed for the effectiveness of the therapy. Results: Comparison between pre and post intervention Indian autism rating scale for autism shows extremely significant result (<0.0001). Conclusion: Improvement in social interaction in children with autism when treated with group therapy.