The present paper deals with the chemical quality delineation of groundwater of the Datana-Palkhana Sector, Ujjain district of Madhya Pradesh. The groundwater samples collected from 40 open dug wells, during the post-monsoon season have been analyzed by adopting standard methods of chemical analysis. The physical parameters of groundwater indicate that all samples are colourless, odourless, and tasteless. The other physical parameters include the pH (7.00 - 8.60), Electrical conductivity (398 - 2090) and Total Dissolved Solids (352 - 1432 ppm). The chemical analysis involves determination of ionic concentration of Ca (38 - 170 ppm), Mg (21- 84 ppm), K (0.9 – 62.24 ppm), Na (20 – 193 ppm), Cl (42- 368 ppm), SO4 (11- 223 ppm), HCO3 (207 - 497 ppm), NO3 (0.9 – 39.90 ppm), and F (0.3 – 1.36 ppm). The suitability of groundwater for irrigation use evaluated based on sodium percent; Kelley’s Ratio, Sodium Adsorption Ratio, Residual Sodium Carbonate, and Magnesium-Hazard. The plots of chemical parameters on U. S. Salinity diagram indicate that 09 samples belong to the C2 S1 type (medium salinity – low sodium water) and 31 samples represent to C3 S1 type (high salinity – low sodium water). Wilcox diagram exhibits that most 09 samples of the groundwater characterize the excellent to good, 30 samples represent the good to permissible and 1 sample is preferable to doubtful to unsuitable categories. In general, the groundwater of the study area is suitable for the irrigation application.