Self is the integrity of organized thoughts, emotions and behavior shaped during bio psychosocial development of the individual and rooted in the family. Self-esteem is the condition of finding one’s self acceptable, valuable and worthy of liking and love without conceiving self below or above the reality. Since the concept of self-shapes the thought and memory, prevention and healing psychological problems concerning self would help remove certain unconformities. Adolescents with a positive self-esteem would cope with the problems of this period more easily and realize their future expectations with hope. Hope is considered as the positive expectation in accomplishing a goal. On the other hand, despair reflects negative and below zero expectations in realizing a goal. The most important characteristics of despair are negative attitudes against perception of life, negative approach and failure. Due to its well-known significance in loss of attention, lack of energy and clinical depression, despair is considered among depressive symptoms. An individual with low self-esteem also has low self-confidence and fells into despair easily.