Dengue viral infections are among the most important mosquito-borne diseases of the Indian subcontinent and have become a major global public health concern. Present study describes clinical profile, trend and outcome of Dengue Fever cases admitted at tertiary care hospital, Rajkot, Gujarat, 2014. A cross-sectional prospective study was conducted at PDU Government Medical College, Rajkot during 1^st January to 31^st December, 2014. All confirmed Dengue cases were admitted in this institute during 2014 included in the study. This study included 145 patients. 62% were males. 69% were in the age group 15-44 yrs. 59% cases were from rural origin. During September to December, 2014, 80% cases were admitted. Fever was present in all the cases i.e. (100%). Most common complication was bleeding from nose and mouth i.e. (66%). Majority of the cases presented with Classical Dengue fever i.e. (90%) followed by Dengue haemorrhagic fever (10%). No any death due to Dengue was reported during study period. 93% cases were discharged from this institute.