The importance of plants in the management of diseases, as well as provision of raw materials for the pharmaceutical industries could not be over emphasized. Crataegus species are part of the important plant family Rosaceae. Members of the genus have been popular for their long term history of use in the treatment and control of metabolic as well as endocrine diseases that are detrimental to humans. It is because of their widely reported pharmacological activities that this review was conducted, in order to have a compilation of the activities of some of the investigated plants of the genus. Google scholar, Science direct, WEBMD, Drugs.com, among other sources, were visited in obtain first hand and genuine information on the pharmacological activities of the plants. Due to extensive research on some particular as well as most popular plants of the genus, the number of plants covered by this review stood at seven (7), though with so many therapeutic potentials.