This prospective study was done to evaluate the anatomic characteristics and the variations of the Sino-Atrial Nodal Artery (SANA) in the North Indian population using an electrocardiographic (ECG)-gated Multi-Detector Computed Tomographic (MDCT) coronary angiography. The ECG-gated MDCT coronary angiograms of 50 subjects [32 males (14-75 years) &18 females (12-70 years); mean age 51.36 ± 14.07 years, age range 12-75 years] were analyzed . Each angiogram was visualized to see the origin of SANA and to determine its number. The correlation of origin of SANA with coronary dominance was also established. Single Sino-atrial nodal artery was seen in 45 (90%) cases and two Sino-atrial nodal arteries were seen in 2 (4%) cases. In 3 (6%) cases, SANA was not visualized. Out of 45 subjects having single SANA, 36 (72%) subjects had origin of SANA from the right coronary artery (RCA), in 2 (4%) cases; the SANA was seen arising from anterior aortic sinus (AAS) and in 7 (14%) cases the SANA arose from left circumflex (LCX) artery. In one case of SANA arising from AAS, it was anomalous and aneurysmally dilated, forming a fistulous tract communicating with the right atrial cavity. In subjects having two Sino-atrial nodal arteries, one arose from RCA and second from LCX artery. SANA was a branch of the dominant artery in 70% cases. This study can provide basic data on normal anatomy and variations of SANA in the North Indian population.