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VOL. 2, ISSUE 2 (2015)
Alcoholic liver disease -- Clinical profile and correlation of severity with the help of electrocardiography
Authors
Ashish Singhal, Hemant Kumar Jain, Omprakash Jatav
Abstract
Background: alcohol affects liver, and affects heart also so we tries to correlates these cardiac changes with severity in patients of alcoholic liver disease patients. Material and methods: The present study entitled has been conducted in Department of Medicine, Jayarogya group of hospitals, GRMC Gwalior M.P. from Nov. 2012 to Nov. 2013.The present study consisted of 102 chronic liver disease patients without any evidence of prior cardiac dysfunction and were evaluated by using electrocardiography. Results: Majority of the patients (80%) are 30-60 years old. Among Group I (ALD) patients (n=68), maximum 32(47%) belongs to child class C. Similarly, among Group II (NALD) patients (n=34),16(47%) belongs to child class C. Abdominal distension is the most common presenting symptom in the study population present in 73.5% of patients followed by swelling over legs in 35.2% of patients & yellowish discoloration of eyes & abdominal pain in 18.6% of patients. Icterus is the most common clinical sign seen in 63 patients followed by ascites in 53 & edema in 28 patients. In the study population,14 patients had no Coronary risk factors, 45 have one Coronary risk factors; 36 had two Coronary risk factors; 6 had three Coronary risk factors; 1 had four Coronary risk factors. Majority of them had dyslipidemia (61 patients) followed by smoking history (34 patients) & diabetes (17 patients).ECG abnormalities correlated significantly with history of alcoholism with abnormal ECG recorded in 67.7% of Group I (ALD) patients as compared to 53% of Group II (NALD) patients.Among the Group I (ALD) patients significantly, 50% had prolonged QTc as compared to 29.4% of Group II (NALD) patients.ECG abnormalities correlated significantly with severity of liver disease in the Group I (ALD) with 4 of Child A patients had abnormal ECG as compared to 17 of Child B & 27 of Child C patients. In the Group I (ALD) only 1 of Child A patients had prolonged QTc as compared to 6 of child B & 27 of Child C patients which was significant.In Group I (ALD) 62 patients had abnormal ECG out of them 28 had two or more Coronary risk factors thus showing the strong association between them. Conclusion: ECG correlates with ALD patients severity.
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Pages:541-549
How to cite this article:
Ashish Singhal, Hemant Kumar Jain, Omprakash Jatav "Alcoholic liver disease -- Clinical profile and correlation of severity with the help of electrocardiography". International Journal of Multidisciplinary Research and Development, Vol 2, Issue 2, 2015, Pages 541-549
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