Aim: To assess the haematological profile in chronic liver disease patients.rnObjectivesrn1) To detect the abnormalities of rbcs in a chronic liver disease patient.rn2) To find the type of anaemia in patient with chronic liver disease and comparison between alcoholic and non-alcohalic chronic liver disease patient. rnMaterials and methodsrn1) To asses type of anaemia in chronic liver disease. The study was conducted J.A. Group of Hospital during the period of June 2013 to November 2014.rn2) About 100 patients of chronic liver disease with anaemia were selected in random from patients coming to department of general medicine opd and ward patients. rnConclusion: Normocytic normochromic anaemia was predominant in overall chronic liver disease patients and Normocytic normochromic anaemia was also predominant in both alcoholic and nonalcoholic chronic liver disease group. While Macrocytic anaemia prevalence was higher in Alcoholic chronic liver disease patients than nonalcoholic group. MCV increases and haemoglobin decreases with the severity of Child Pugh score especially in alcoholic chronic liver disease so we can say that macrocytic anaemia increases with severirty of alcoholic chronic liver disease. Early detection and treatment of haematological changes can prevent complications and reduce the mortality in CLD patients.