The effects of diazepam anesthesia in total blood protein and blood glucose was determined in six adult, healthy West African dwarf goats weighing 13kg to 16kg were used. Anesthesia was induced using 0.25mg/kg diazepam intravenous injection. Total blood protein and blood glucose analysis were performed before anesthesia (To), 2 hours, 24 hours, 5 days and 7 days after recovery. Effects on clinical parameters the result indicated that there were no significant changes in hemoglobin and albumin concentrations while in glucose there was significant decreased at 2 hours and 24 hours after recovery. It is therefore concluded that diazepam as a single dose can be used to induce short-term anesthesia in goats with minimum effects on clinical parameters..