The outcome of students’ performance at certificate examinations in physics recently has not justify the efforts put into its study. The consequent of this would implies failure in achieving the purpose of studying physics at the secondary school level and invariably affects the national technological growth plan. The attitude of students to practical aspect of physics appears not encouraging. This study analysed factors that are influencing students’ attitudes towards physics practical in secondary schools in Ekiti state. It was a survey type of descriptive research design. The sample for the study comprised 1200 physics students selected from 48 secondary schools in Ekiti state. Three research questions were raised for the study, which were answered using descriptive analysis of mean and percentages. A self-developed questionnaire was used to collect data from the respondents. Analysis of the data showed that the students attitudes towards physics practical in secondary schools in Ekiti state include being scared by the measurements involved, lack of interest, annoyance during physics practical classes and therefore do not prepare for them. Also, the factors influencing students’ attitudes towards practical aspect of secondary school science in Ekiti state can be categorized into students-related factors, teachers-related factors and laboratory related factors. Based on this, recommendations were made to positively change the attitudes of the students towards practical aspect of secondary school physics in Ekiti state.