Purpose: To report a case of isolated cilioretinal artery occlusion in a 55 years old man. Methods: A 55 years old man presented with sudden, painless diminution of vision in the left eye since one day. Best corrected visual acuity was 20/20, N6 in the right eye and Counting Fingers at 0.5 metres in the left eye. Anterior segment examination was normal. Fundus examination of the left eye revealed an occluded cilioretinal artery with an area of papillomacular infarction and macular oedema. OCT confirmed intraretinal oedema in the area of the infarct. Glycosylated hemoglobin was 8.1%, Fasting blood sugar was 107 mg/dl while the post prandial blood sugars were 257 mg/dl. Carotid Doppler was within normal limits. He was started on oral hypoglycemic agents and aspirin 75 mg OD by the physician.rnResults: By 3 weeks, he regained left eye vision to 20/30, N6.The patient was lost to follow up after 4 visits. rnConclusion: Prophylactic aspirin may have a role in early visual recovery in isolated cilioretinal artery occlusion.