This study investigated the accessibility and use of serials and other continuing resources in two universities in North-Central zone of Nigeria. It sought to determine the accessibility of serials and other continuing resources, examine the use of serials and other continuing resources, identify the problems affecting use of serials and other continuing resources and proffer necessary strategies for enhancing use of serials and other continuing resources. A descriptive survey design was used for the study with a population of 1500 library users. Sample size of 300 representing 20% of the population was used for the study. The instrument for data collection was structured questionnaire. Percentages, mean scores and frequency tables were used in analyzing the data. The result obtained from the findings revealed that both serials and other continuing resources are accessible. It was equally found that the patrons make use of serials and other continuing resources. The study also shows that some of the difficulties encountered in accessing and using serials and other continuing resources includes but not limited to lack of borrowing facilities in serials section, inconvenient open/closing hours of serials, poor attitude of staff to users, inadequate reading facilities in the serials section, Power failure and poor network connection. Conclusion and recommendations were made based on the findings.