Background – We studies clinical profile of organophosphorous poisoning in our institute. Material And Methods – This open prospective study was conducted IN THE DEPARTMENT OF MEDICINE, GRMC, GWALIOR, All patients admitted IN J.A. GROUP OF HOSPITALS from nov 2012 to oct. 2013 were studied. Out of total 218 patients, 91 patients who gave consent and fit in inclusion criteria were taken for the study and rest who refused to give consent and having character of exclusion criteria were excluded from the study. Results- Males of age group 21-30 years, from rural population in our study were mainly affected by OP poisoning, and most patients belongs to low to middle class of society. Most patients were mildly affected. But most death were in severe toxicity group. Hypokalemia was most common electrolyte imbalance and QTc prolongation was mostly associated with mortality and significantly associated with the complications. Conclusion- Organophosphorous poisoning is major poisoning in India and early hospitalization, correction of hypokalemia and QTc prolongation could be life saving in these patients.