The present paper presents a high performance instrumentation amplifier based on operational amplifier (op-amp) for low power applications. This instrumentation amplifier (IA) is designed for low power while maintaining the high PSRR, high CMRR as well as other design constraints. The Most effective topology current feedback is illustrated in this article using some dynamic techniques for offset & noise compensation. Current feedback chopper stabilization technique has been widely used in amplifiers which are based upon the principles of modulation and demodulation. Thus, the functionality and overall performance of MODEM circuits determines the realization and attainment of chopper stabilization for flicker (1/f) noise and offsets reduction purposes. A different technology variation 800nm to 180nm has been introduced in this review to design precise instrumentation amplifier.