The study attempts to present a holistic description of Personal pronouns in Assamese encompassing their typological classification, morphological variations, syntactic functions, inherent semantic interpretations and use in different context of discourse. Assamese is a Neo-Indo Aryan language, recognized by the constitution of India as one of the official languages spoken in Assam. According to census report of 2011, the total number of native speakers of Assamese being 16.8 million and Assamese is spoken by over 20 million people belonging to heterogeneous speech communities living together. Assamese has been used as a lingua-franca among the non-native speakers of Assam for centuries in respect of trade and commerce, monetary transactions and social contacts. Assamese is agglutinative with a SOV word order. It is a language with nominative and accusative features. The language exhibits subject verb agreement. Personal pronouns play an important role in the language.