The bioactive components of Clerodendrum phlomidis leaf have been evaluated using GC/MS. The chemical compositions of the methanol extract of Clerodendrum phlomidis leaf was investigated using Perkin-Elmer Gas Chromatography–Mass Spectrometry, while the mass spectra of the compounds found in the extracts were matched with the National Institute of Standards and Technology (NIST) library. GC/MS analysis of methanolic extract of Clerodendrum phlomidis revealed the existence of sixty nine compounds in leaf. The prevailing compounds of Clerodendrum phlomidis leaves were α – terpinene (RT 3.692), 4H-Pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl- (RT 33.142), Ethyl iso-allocholate (RT 35.367), Phytol isomer (RT 36.846). The results of this study offer a platform of using of Clerodendrum phlomidis leaf as herbal alternative for various diseases.