The antibiotic resistance that is developing globally in disease-causing bacteria is one of the major threats to human medicine. It leads to additional burdens on health systems, to treatment failures and, in the worst cases, to untreatable infections or infections treated too late to save life. Although the over-use of antibiotics in human medicine is the major cause of the current crisis of antibiotic resistance, public-health experts are agreed that the over-use and mis-use of antibiotics in intensive animal production is also an important factor – around half of the world’s antibiotic production is used in farm animals. Ciprofloxacin is a case in point. Our study focused on square wave voltammetry or electrochemistry for screening ciprofloxacin residue in black tiger shrimp. This is evaluated as a promising application for small – medium enterprises in controlling antibiotic residues in general and ciprofloxacin in particular.