Impact of Hexavalent chromium on the Testicular lipogenic and lipolytic Enzymes in Albino rats
M. Santhosh Kumar, C. Siva
Chromium constitutes one of the heavy metals that are largely disposed to the environment through tannery wastes and from metallurgic, refractory and chemical industries. In this compounds denoted chromium (hexavalent compounds). In the present study, an attempt is made to know the chromium-induced cytotoxicity on the testis of pubertal albino rats. Since the reduction of chromium inside the cells, brings about various biochemical modifications, chromium-induced cytotoxicity on testis can be studied well by treating rats with chromium-mixed water. The general metabolism and steroidogenic processes of the testis, an attempt made to know the impact of chromium on these testicular lipogenic enzymes.The direct effects of chromium-induced cytotoxicity on the testicular architecture, lipogenic processes of the testis and serum hormonal profiles in these pubertal rats in a dose-dependent manner. Due to these deleterious effects of chromium-induced cytotoxicity, the spermatogenic and steroidogenic processes in the testis may get impaired, leading to infertility.